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Jean George Bachmann
(1877 – 1959)
French physician–physiologist whose experimental work in the early twentieth century provided the first clear functional description of a preferential interatrial conduction pathway. This structure, eponymically named “Bachmann’s bundle”, plays a central role in normal atrial activation and in the pathophysiology of interatrial block and atrial arrhythmias.
As a young man, Bachmann served as a merchant sailor, crossing the Atlantic multiple times. He emigrated to the United States in 1902 and earned his medical degree at the top of his class from Jefferson Medical College in Philadelphia in 1907. He stayed at this Medical College as a demonstrator and physiologist. In 1910, he joined Emory University in Atlanta. Between 1917 -1918 he served as a medical officer in the US Army. He retired from Emory in 1947 and continued his private medical practice until his death in 1959.
On the personal side, Bachmann was a man of many talents: a polyglot, he was fluent in German, French, Spanish and English. He was a chef in his own right and occasionally worked as a chef in international hotels. In fact, he paid his tuition at Jefferson Medical College, working both as a chef and as a language tutor.
The intrinsic cardiac conduction system was a major focus of cardiovascular research in the late nineteenth and early twentieth centuries. The atrioventricular (AV) node was discovered and described by Sunao Tawara and Karl Albert Aschoff in 1906, and the sinoatrial node by Arthur Keith and Martin Flack in 1907.
While the connections that distribute the electrical impulse from the AV node to the ventricles were known through the works of Wilhelm His Jr, in 1893 and Jan Evangelista Purkinje in 1839, the mechanism by which electrical impulses spread between the atria remained uncertain.
In 1916 Bachmann published a paper titled “The Inter-Auricular Time Interval” in the American Journal of Physiology. Bachmann measured activation times between the right and left atria and demonstrated that interruption of a distinct anterior interatrial muscular band resulted in delayed left atrial activation. He concluded that this band constituted the principal route for rapid interatrial conduction.
Subsequent anatomical and electrophysiological studies confirmed the importance of the structure described by Bachmann, which came to bear his name. Bachmann’s bundle is now recognized as a key determinant of atrial activation patterns, and its dysfunction is associated with interatrial block, atrial fibrillation, and abnormal P-wave morphology. His work remains foundational in both basic cardiac anatomy and clinical electrophysiology.
Sources and references
1. Bachmann G. “The inter-auricular time interval”. Am J Physiol. 1916;41:309–320.
2. Hurst JW. “Profiles in Cardiology: Jean George Bachmann (1877–1959)”. Clin Cardiol. 1987;10:185–187.
3. Lemery R, Guiraudon G, Veinot JP. “Anatomic description of Bachmann’s bundle and its relation to the atrial septum”. Am J Cardiol. 2003;91:148–152.
4. "Remembering the canonical discoverers of the core components of the mammalian cardiac conduction system: Keith and Flack, Aschoff and Tawara, His, and Purkinje" Icilio Cavero and Henry Holzgrefe Advances in Physiology Education 2022 46:4, 549-579.
5. Knol WG, de Vos CB, Crijns HJGM, et al. “The Bachmann bundle and interatrial conduction” Heart Rhythm. 2019;16:127–133.
6. “Iatrogenic biatrial flutter. The role of the Bachmann’s bundle” Constán E.; García F., Linde, A.. Complejo Hospitalario de Jaén, Jaén. Spain
7. Keith A, Flack M. The form and nature of the muscular connections between the primary divisions of the vertebrate heart. J Anat Physiol 41: 172–189, 1907.
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UPDATED: This medical term is formed by the prefix [retr-] meaning “posterior”, the root term [-periton-] meaning “peritoneum”, and the adjectival suffix [-eal], meaning “pertaining to”. In the strictest sense, the term [retroperitoneal] means “posterior to the peritoneum”.
In practical terms in anatomy and surgery, this term refers to two situations:
In the first acception of the term, it refers to anatomical structures that are truly posterior to the peritoneum, between the peritoneum and the posterior abdominal wall, as are the kidneys, ureters, abdominal aorta, inferior vena cava, etc.
In the second acception of the term, it refers to digestive system structures that although posterior to the parietal peritoneum, they are also attached to the posterior abdominal wall by the peritoneum, fixating them to the posterior abdominal wall. These structures are immobilized in position by the peritoneum. When a surgeon needs to work on one of these “retroperitoneal” digestive system structures they need to render them mobile detaching them from the posterior abdominal wall by incising the peritoneum and “mobilizing “these structures.
There are three segments of the digestive system that are retroperitoneal (ergo, fixated to the posterior abdominal wall by the parietal peritoneum):
- the duodenum, except for its first inch
- the ascending colon
- the descending colon
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Dr. Jean Léo Testut
Jean Léo Testut (1849-1925) French physician, anatomist, historian, and anthropologist, Jean Léo Testut Deynat was born in Saint Avit Senier, France on March 22, 1849.
His early medical studies were interrupted by the Franco-Prussian war of 1870. He was awarded a medal for his courage and patriotism in this war, but declined to accept it. After the war Leo Testut finished his medical studies in 1878 at the Medical School in Bordeaux. His doctoral thesis received several awards, including the Silver Medal of the Paris Medical College.
During his medical studies at the Universities of Bordeaux and Paris, Testut was an assistant for both anatomy and physiology, eventually becoming the Chief of Anatomical Studies and Preparations in Bordeaux.
In 1887 he publishes his masterpiece: “Traité d'anatomie humaine” (Human Anatomy Treatise) in four volumes, which has a second publication in 1893.
Dr. Testut's assistant, Dr. André Latarjet (1877 – 1947) will later continue the work in this voluminous work taking it to five volumes, several editions, and translated into Spanish, German, and Italian. Smaller versions of the book as well as anatomical dissectors are published as companions to this superb book, becoming the standard of anatomical medical education in France and especially in Latin America for over 120 years.
In spite of this incredible publication, Leo Testut published well over 90 books and treatises, including an illustrated anatomical dissector. His work included anthropological research and comparative anatomy.
Dr. Testut worked as a military surgeon during World War I.
In his later life Dr. Testut received an incredible number of awards and decorations, including the Honor Legion Medal and Honorary Professor of the Lyon Medical School. He was also President of the World Association of Anatomists.
After he retired, he continued his historical studies publishing a further seven books!
Personal note: When I studied anatomy I was lucky to use the Testut and Latarjet “Compendio de Anatomía Humana”, the smaller version of the Treatise. The Treatise itself was available to us for study in the library of the Medical School at the University of Chile and I remember countless hours studying with this treasure of anatomy. Later I made it a point to own one of these incredible books, and I acquired the Spanish and the Italian version of the “Traité d'anatomie humaine”. A few years ago I added to my library a beautiful leather-bound French version of this book, which belonged to my dear friend Dr. Gonzalo Lopetegui Adams (1932 – 2004). Dr. Miranda.
Sources:
1. “Leo Testut (1849-1925)” Reverón, RR Int. J. Morphol., 29(4):1083-1086, 2011
2. “La anatomía de Testut y Latarjet” Reverón, RR R Soc Ven Hist Med (2013) 62:1; 62-72
3. “Jean Leo Testut (1849-1925): Anatomist and Anthropologist” Reverón, RR
4. “Huellas de un maestro de la Anatomía francesa: Jean Léo Testut, 1849-1925” Ledezma W.; P. Rev Inst Med Sucre LXXI: 128 (98-105), 2006
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This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.
Dr. Václav Treitz
UPDATED: Dr. Václav Treitz (1819 - 1872). Also known as Wenzel Treitz, Dr. Václav Treitz was born in Hostomice, Bohemia. He attended the Charles-Ferdinand University in Prague studying humanities and medicine, receiving his medical degree in 1846. Treitz started postgraduate work at the Vienna General Hospital (Allgemeines Krankenhaus), where Joseph Skoda (1805-1881) was a proponent of “therapeutic nihilism” which stated that “drug treatment usually does more harm than good”, so a minimalistic or even pessimistic approach to diseases was used.
Large numbers of women at this hospital died of “puerperal fever” an postpartum uterine infection due to contamination by the unwashed hands of physicians and utter lack of cleanliness (septic technique had not been yet described). It was during Treitz’s time at the Vienna General Hospital that Ignaz Philipp Semmelweis (1818 – 1865) stated his initial observations on asepsis. Treitz later became a follower of Semmelweis’ and Lister’s teachings and techniques.
In 1852 Treitz was appointed Professor of Pathological Anatomy in the Jagellonian University in Prague.
In 1853 he published a paper ("Ueber einen neuen Muskel am Duodenum des Menschens" ) describing a new muscle he discovered at the duodenojejunal junction, later to be known as the eponymic “muscle of Treitz”; the fold of peritoneum over the muscle of Treitz is known today as the "ligament of Treitz". Treitz also described a paraduodenal retroperitoneal hernia that occurs at the paraduodenal recess, just lateral to the ligament of Treitz.
A staunch proponent of Czechoslovakian independence and language, Treitz was publicly attacked for his medical theories and nationalistic beliefs. Isolated and depressed, Treitz committed suicide in 1872.
The article on the "Ligament of Treitz" is the most popular article in "Medical Terminology Daily" with over 140 thousand hits!
Sources:
1. "Václav Treitz (1819-1872): Czechoslovakian Pathoanatomist and Patriot” Fox, RS; Fox, CG; Graham, WP. World J. Surg. 9, 361-366, 1985
2. "Treitz of the ligament of Treitz". Haubrich, W S. (2005) Gastroenterology, 128 (2), 279
3. "Preserving Treitz's muscle in hemorrhoidectomy". Gemsenj?ger, E Diseases of the Colon & Rectum (1982), 25 (7), p. 633.
4. “The Muscle Of Treitz And The Plica Duodeno-Jejunalis” Crymble, PT. The British Medical Journal, Vol. 2, No. 2598 (1910), 1156-1159
Original image, public domain, courtesy of Wikimedia Commons.
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Obturator foramen
The word [foramen] is a Latin word meaning "opening, aperture, hole", from the Latin term [forare] meaning to bore a hole, to pierce. The plural form of the word is [foramina]. There are many foramina in the human body.
• Epiploic foramen (of Winslow): An opening bound by the lesser omentum, the inferior vena cava, duodenum and liver. It is a communication between the main peritoneal cavity and lesser sac, an area found posterior to the stomach.
• Nutritional foramina: Openings found in most bones allowing for passage of blood vessels.
• Obturator foramen: An opening in the pelvis bound by the following bones: ilium, ischium, and os pubis. Indicated in the accompanying image by an arrow.
• Foramen of Monro: A communication between the lateral ventricle and the third ventricle of the brain. There are actually two foramina of Monro (one on each side), and are important for cerebrospinal fluid circulation. Named after Alexander Monro Secundus (1733 - 1817).
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UPDATED: Root term meaning Thorax (Greek: [θώρακα] Chest plate or area covered by a chest plate). The thorax contains three areas, or regions, sometimes described as "spaces" (sic). These are two laterally situated pleural cavities, each containing a lung, and a median mediastinum, a large region containing the pericardium, heart, great vessels, thoracic duct, azygos venous system, esophagus, aorta, thymus, etc. The plural form for thorax is [thoraces].
• Thoracotomy: Opening of the thorax. Note that the term "thoratomy" en vogue nowadays is a misuse of the term
• Thoracocentesis: The suffix [-(o)centesis) means needle aspiration. Needle aspiration of the thorax
• Thoracoscopy: Visualization of the thorax
Personal note: There is a tendency, a trend to use the word [thorascopy] instead of the correct form [thoracoscopy]. The use of [thorascopy] is incorrect and should not be allowed in the clinical arena. In fact, it is not recognized by my medical spellchecker! Dr. Miranda
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This suffix originates from two Greek root terms [ectos], meaning "out or outside" and "[tomos], which means "to cut" or "to open". The final [-y] means "process". The suffix [-ectomy] means "process of cutting out". Other synonyms are: extirpation, excision, and removal.
Applications of this suffix include:
- Pneumonectomy: Removal of a lung
- Gastrectomy: Extirpation of the stomach
- Nephrectomy: Excision of a kidney
- Cholecystectomy: Extirpation of the gallbladder