Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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Inferior vena cava

Anterior view of the IVC. Gray, 1918
Click for a larger image

The inferior vena cava (IVC) in one of the great vessels. It brings deoxygenated blood from the lower extremities, pelvis, and areas of the abdomen to the right atrium of the heart.

As a side note, the blood returning from the digestive system does not usually enter the IVC. It has it its own venous subsystem converging into the liver by way of the portal vein.

The IVC is formed by the confluence of the right and left common iliac veins. This lower end of the inferior vena cava is found anterior to the L4-L5 intervertebral disc. The IVC covers the superior aspect of the body of L5.

The IVC ascends to the right of the abdominal aorta and anterolateral to the vertebral bodies. It receives several branches as it passes superiorly:

• Common iliac veins
• Lumbar veins
• Gonadal veins
• Renal veins
• Right suprarenal veins
• Hepatic veins
• Inferior phrenic veins

As the IVC passes posterior to the liver, it is hugged by the mass of the posterior aspect of the liver, it will receive the hepatics veins, and pass through the IVC hiatus of the respiratory diaphragm, entering immediately into the right atrium of the heart. At this point the IVC will present an incomplete venous valve known as the Eustachian valve, named after Bartolomeo Eustachius (c1500 - 1574).

Sources:
1. "Tratado de Anatomia Humana" Testut et Latarjet 8 Ed. 1931 Salvat Editores, Spain
2. "Gray's Anatomy" 38th British Ed. Churchill Livingstone 1995
3. "Reconstructive Anatomy: A Method for the Study of Human Structure: Arnold, M WB Saunders1968
Image modified from the original by Henry VanDyke Carter, MD. Gray's Anatomy.