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Jean George Bachmann
(1877 – 1959)
French physician–physiologist whose experimental work in the early twentieth century provided the first clear functional description of a preferential interatrial conduction pathway. This structure, eponymically named “Bachmann’s bundle”, plays a central role in normal atrial activation and in the pathophysiology of interatrial block and atrial arrhythmias.
As a young man, Bachmann served as a merchant sailor, crossing the Atlantic multiple times. He emigrated to the United States in 1902 and earned his medical degree at the top of his class from Jefferson Medical College in Philadelphia in 1907. He stayed at this Medical College as a demonstrator and physiologist. In 1910, he joined Emory University in Atlanta. Between 1917 -1918 he served as a medical officer in the US Army. He retired from Emory in 1947 and continued his private medical practice until his death in 1959.
On the personal side, Bachmann was a man of many talents: a polyglot, he was fluent in German, French, Spanish and English. He was a chef in his own right and occasionally worked as a chef in international hotels. In fact, he paid his tuition at Jefferson Medical College, working both as a chef and as a language tutor.
The intrinsic cardiac conduction system was a major focus of cardiovascular research in the late nineteenth and early twentieth centuries. The atrioventricular (AV) node was discovered and described by Sunao Tawara and Karl Albert Aschoff in 1906, and the sinoatrial node by Arthur Keith and Martin Flack in 1907.
While the connections that distribute the electrical impulse from the AV node to the ventricles were known through the works of Wilhelm His Jr, in 1893 and Jan Evangelista Purkinje in 1839, the mechanism by which electrical impulses spread between the atria remained uncertain.
In 1916 Bachmann published a paper titled “The Inter-Auricular Time Interval” in the American Journal of Physiology. Bachmann measured activation times between the right and left atria and demonstrated that interruption of a distinct anterior interatrial muscular band resulted in delayed left atrial activation. He concluded that this band constituted the principal route for rapid interatrial conduction.
Subsequent anatomical and electrophysiological studies confirmed the importance of the structure described by Bachmann, which came to bear his name. Bachmann’s bundle is now recognized as a key determinant of atrial activation patterns, and its dysfunction is associated with interatrial block, atrial fibrillation, and abnormal P-wave morphology. His work remains foundational in both basic cardiac anatomy and clinical electrophysiology.
Sources and references
1. Bachmann G. “The inter-auricular time interval”. Am J Physiol. 1916;41:309–320.
2. Hurst JW. “Profiles in Cardiology: Jean George Bachmann (1877–1959)”. Clin Cardiol. 1987;10:185–187.
3. Lemery R, Guiraudon G, Veinot JP. “Anatomic description of Bachmann’s bundle and its relation to the atrial septum”. Am J Cardiol. 2003;91:148–152.
4. "Remembering the canonical discoverers of the core components of the mammalian cardiac conduction system: Keith and Flack, Aschoff and Tawara, His, and Purkinje" Icilio Cavero and Henry Holzgrefe Advances in Physiology Education 2022 46:4, 549-579.
5. Knol WG, de Vos CB, Crijns HJGM, et al. “The Bachmann bundle and interatrial conduction” Heart Rhythm. 2019;16:127–133.
6. “Iatrogenic biatrial flutter. The role of the Bachmann’s bundle” Constán E.; García F., Linde, A.. Complejo Hospitalario de Jaén, Jaén. Spain
7. Keith A, Flack M. The form and nature of the muscular connections between the primary divisions of the vertebrate heart. J Anat Physiol 41: 172–189, 1907.
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Most medical words have only one root term and do not require combination as in the word [colectomy]. The situation arises when there is more than one organ or structure that is influenced by the suffix and the prefix (when present), such as [coloproctectomy]. Following are the basic rules for root terms combination:
- - Place an [-o-] between the root terms being combined. The combining vowel [o] means "and". The word [gastroenterology] means "study of the stomach and the small intestine"
- - Organize the root terms using their proximal to distal relationship. For a better explanation, click here
- - If the first root term ends in a vowel, the combining vowel [-o-] is not needed. An example are the root terms [-chole-], meaning "bile or gall". and [cyst], meaning "bladder or sac". The word [chole-cyst-ectomy] does not have an [-o-] between the root terms
- - If the proximal to distal relationship does not apply, then the words should be ordered in a way that is euphonic
- - The only time a hyphen should be used is the rare case when using an [o] is not possible. Based on this rule, the word [salpingooophorectomy] is correct, the word [salpingo-oophorectomy] is not. An example of this is the word [cross-section].
An example of rule #5 is the word co-author. Since adding an [o] as a combining vowel would give us the word cooauthor (which is not correct), a hyphen must be used.
In the case of the word [coloproctectomy] the word can be divided into these components" The first root term [-col-], meaning "colon", the combining vowel [-o-], meaning "and", the second root term [-proct-], meaning "rectum", and the suffix [-ectomy], meaning "removal of". Properly read, the word means "removal of colon and rectum]. The proper term is [coloproctectomy], please do not use the terms [proctocolectomy] or worse, [protocolectomy], because they are incorrect usage of medical terminology.
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In medical terminology there are many adjectival suffixes that transform a root term into an adjective. In general these adjectival suffixes have the meaning of "pertaining to", and complete the word. In many cases the adjectival suffix can be omitted and simply refer to the root term.
An example of this is the suffix [-ic] in the word [gastric], added to the root [-gastr-] meaning "stomach". The word [gastric] then means "pertaining to the stomach", or more simply stated, "stomach". The following lists some of the adjectival suffixes and examples of its use. For brevity, we have not given the root term meaning, but they can be inferred.
• -ic: Gastric; pertaining to the stomach, stomachal, or stomach
• -eal: Esophageal; pertaining to the esophagus, or esophagus
• -ar: Ocular; pertaining to the eye, or eye
• -ose: Adipose; pertaining to, or full of, fat. Refers to fat or fatty tissue
• -ine: Uterine; pertaining to the uterus or uterus
• -al: Surgical; pertaining to surgery or surgery
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The suffix component of a word is found at the end of a medical word after the root term(s) and also alters or influences the meaning of the root term. In the words [planter], [planted], and [planting] the suffixes are [-er], [-ed], and [-ing]. Some of the most simple suffixes are adjectival suffixes such as [-ic], [-al], [-eal], etc. all of them meaning "related to" or "pertaining to".
In medical terminology, the use of each root term can be multiplied many times over by the addition of prefixes and suffixes. Using the root term [-gastr-], meaning "stomach", we can form: [gastric], [gastritis], [gastrotomy], [gastrectomy], [gastrostomy], [gastrorrhaphy], [gastrography], [gastroscope], [gastroscopy], [gastropod], [gastroma], [perigastritis], [endogastritis], [intragastric], [epigastric], etc.
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The listing of medical suffixes is quite large and should be mastered by professionals in the medical industry. Medical Terminology is one of the core competencies of CAA, Inc.
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All words have a foundation, called a root or a root term. The root is the minimal expression of a word that conveys a specific meaning. The word [hepa] does not mean liver, but the root term [-hepat-] does. There are some root words that have two presentations, like [-card-] and [-cord-], both meaning "heart", and even three presentations such as [-uter-], [-metr-], and [-hyster-], all of them meaning "uterus". All these following words have root terms meaning "uterus": periuterine, endometrium, and hysterectomy.
As an example, all the following medical terms: [pneumonectomy], [pneumonia], [pneumonitis], [pneumogastric], [pneumobacillus], and [pneumothorax] have the same common root term [-pneumon-], from the Greek [πνεύμονας], meaning "lung".
In medicine, surgery, and human anatomy there are several cases where there is more than one root term for the same organ. The terms [lienectomy] and [splenectomy] both mean "removal of the spleen", as the root terms [-lien-] and [-splen-] both mean "spleen". The same is the case in the following pairs: [-nephr-] and [-ren-], meaning "kidney"; [-cyst-] and [-vesic-], meaning "bladder"; [-pneumon-] and [-pulmon-], meaning "lung"; etc.
Root terms can also be combined to form complex medical terms, such as [gastroenterology], [leiomyomata], [cholecystectomy], [dacryocystolithectomy], [nephroureterocystourethrectomy], etc. To do this there are specific rules for combination.
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A prefix is a component of a word that precedes the root term and alters or influences the meaning of the root term. The root [port], from the Latin [portare], meaning "to carry" is found in the words export, support, and transport. The prefixes are [ex-], meaning "outside"; [sup-], meaning "above or on top"; and [trans-], meaning "across".
The same is true for medical terms. The words suprahepatic, infrahepatic, and transhepatic, all contain the root term[-hepat-] from the Greek [hepar], meaning "liver". The prefixes are [supra-], meaning "superior or above"; [infra], meaning "inferior or below"; and [trans], meaning "through or across".
For information on how to read medical words, click here.
The listing of medical prefixes is quite large and should be mastered by professionals in the medical industry. Medical Terminology is one of the core competencies of CAA, Inc.
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The word [mesenchymal] is the adjectival form of [mesenchyme] which arises from the Greek combination of [μέσο] (meso) meaning “middle”, and [χυμός] (chymos) meaning “juice”. In the early physiological theory of “humors” it refers to a type of “juicy” organ tissue. These organs needed to be activated by a thick fluid.
The term was used in embryology in 1881 to denote a portion of the mesoderm formed by loose cells that give origin to connective tissues.
The original meaning of the term [mesenchyme] has no application today, except being used to denote a tissue characterized by loose cells that are surrounded by a large extracellular matrix. Mesenchymal cells are able to develop into tissues of the lymphatic and circulatory systems, as well as connective tissues throughout the body, including bone and cartilage.
Some mesenchymal cells in the adult can be harvested and used as somatic stem cells.
Sources:
1. "The Origin of Medical Terms" Skinner, HA 1970 Hafner Publishing Co.
2. "Human Embryology" WLJ Larsen 1993 Churchill Livingstone
Note: The links to Google Translate in these articles include an icon that will allow you to hear the Greek or Latin pronunciation of the word.