Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.
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Georg Eduard Von Rindfleisch
(1836 – 1908)
German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.
He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.
After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.
Associated eponyms
"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.
"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.
Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.
Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999) Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross
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Hyaline cartilage
Cartilage is a type of avascular tissue with a highly specialized extracellular matrix that contains chondrocytes. The condrocytes produce and maintain the extracellular matrix. The root term meaning [cartilage] is [-chondr-], which originatesfrom the Greek [χόνδρος] or [chondros] meaning "cartilage" or "gristle". The Latin equivalent is [cartilago] giving us the synonymous root term [-cartilag-], from which [cartilage] arises.
The matrix contains large amounts of glicosaminoglycans, which allows for easy diffusion of substances from surrounding structures and blood vessels. Being avascular, cartilage does not have its own blood supply. The extracellular matrix also has large quantities of hyaluronic acid, which allows cartilage a weight-bearing capacity. This is why cartilage is particularly useful in bony joints and covering articular surfaces.
There are three types of cartilage present in the human body:
• Elastic cartilage: This type of cartilage is characterized by elastic fibers, usually in layers or lamellae
• Fibrocartilage: This type of cartilage is characterized by large bundles of collagen, making it look and feel fibrous
• Hyaline cartilage: This type of cartilage is characterized by an homogenous amorphous matrix
Thanks to Dr. Stephen Gallik for the mage and links. For more information on mammalian hystology, you can visit Dr. Gallik's website here.
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The root term [-cheil-] derivates from the Greek word [χείλος (keilos]] meaning "lip". There are other medical root terms that also mean lip, but they arise from the Latin words [labellum, labrum, and labra]. There are many medical terms that include the root [-cheil-]:
• Cheilitis: The suffix [-itis] means "inflammation". Inflammation of the lips
• Cheilitis simplex: A very medical way of saying "chapped lips". See accompanying image.
• Cheiloplasty: The suffix [-(o)plasty] means "surgical reshaping". A surgical reshaping or plastic surgery of the lips
• Angular cheilitis: Inflammation of the angle of the mouth, sometimes causing a fissure
• Cheilognathopalatoschisis: This wors combines several roots: [-cheil-], meaning "lip", [-gnath-] meaning "jaw", [-palat-], meaning "palate", while the suffix [-schisis] means "to split". A split or separation of the lip, jaw, and the hard and soft palate.
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The root term [-lapar-] arises from the Greek word [λαπάρα] which means "flank or "loin"". It refers to the lateral region of the abdomen between the costal margin superiorly and the iliac crest inferiorly. In its pure etymological meaning the root term [lapar], as in "laparotomy" or "laparoscopy" should be used to denote a surgical action in only two of the abdominal regions, the right and left lumbar abdominal regions (or flank regions). The suffix [-otomy] originates from the Greek [τέμνω] (tomos) which means "to cut" or "to open".
The first modern use of the term [laparotomy] referring to "an abdominal incision" was in January 1878 by Thomas Bryant, FRCS in his book "A Manual for the Practice of Surgery". This of course caused an upheaval with language purists, as a true laparotomy is a flank incision only. Nonetheless the meaning of the term as suggested by Bryant has been in use since. Today any abdominal incision is a laparotomy.
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This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.
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Giovanni Domenico Santorini (1681 – 1737). Italian anatomist, Santorini was born in 1681 in Venice. The son of an apothecary, Santorini studied medicine at Bologna and Padua, receiving his doctorate in Pisa in 1701. He was appointed Public Professor of Anatomy at the Physicomedical College of Medicine when he was 22 years of age.
Santorini was praised for the clarity of his lectures and his dexterity as an anatomist. He used magnifying glasses to study minute anatomical details, allowing him to clearly describe small structures hitherto unknown. Most of Santorini’s biographical data was written by Michael Girardi (1731 – 1797), one of his students. Girardi published Santorini’s work posthumously in 1775 in the book “Anatomici Summi-Septendecim Tabulae”.
Santorini’s himself wrote “Opuscula medica de structura” (Minute Medical Structures) in 1705. His most important book was “Observationes anatomicae”, published in Venice in 1724. One of the most interesting chapters in this book was “De mulierum partis procreationes datis” (Data on the female procreational structures ), making him a pioneer in the teaching of obstetrics. Santorini was physician to the Spedaletto (Hospital) of Venice, where he taught midwifery.
Santorini died in 1737 because of an infection he acquired during the dissection of a cadaver. At that time the rationale for infection and cadaver embalming were unknown.
With his posthumous publications, Santorini’s name and teachings became popular. Today his name is eponymically tied to several structures in the human body:
• Duct of Santorini: An accessory pancreatic duct that opens into a secondary duodenal papilla in the second portion of the duodenum
• Santorini’s valves: Mucosal folds found in the lumen of the primary duodenal papilla (of Vater) or hepatopancretic ampulla
• Santorini’s muscle: Risorius muscle • Santorini’s cartilages: The laryngeal corniculate cartilages
• Santorini’s veins: A plexus of vesicoprostatic veins found in the retropubic space) of Retzius
• Santorini’s concha: The superior nasal turbinate
Sources:
1. “The Dorsal Venous Complex: Dorsal Venous or Dorsal Vasculature Complex? Santorini’s Plexus revisited” Power NE, et al. BJU Inter (2011) 108: 930-932
2. “Giovanni Domenico Santorini: Santorini’s Duct” Edmonson, JM Gastrointest Endosc (2001) 53:6; 25A
3. "Santorini of the duct of Santorini" Haubrich, WS Gastroenterol 120:4, 805
4. “Wirsung and Santorini: The Men Behind the Ducts” Flati, G; Andren-Sandberg, A. Pancreatology (2002)2:4-11
5. "A Historical Perspective: Infection from Cadaveric Dissection from the 18th to the 20th Centuries" Shoja, MM et al. Clin Anat (2013) 26:154-160
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The [conjoint tendon] (sometimes called the conjoined tendon] is the common tendinous attachment of the internal oblique muscle and the transverse abdminis muscle into the pubic tubercle. Some of these tendinous attachments extend also to the pectineal (Cooper's) ligament, the inguinal ligament, and the superior ramus of the pubic bone. In the classical anatomical description these tendons mix to the point that they cannot be separated one from the other, hence the term [conjoint tendon].
The conjoint tendon is important in open hernia repair, where some surgical techniques require the surgeon to pass a surgical needle and suture through this tendinous structure, to attach or close the gap between the conjoint tendon and the inguinal ligament.
In spite of being described in many anatomy books, a true "conjoint tendon" is only found in about 4% of the cases (varying from 3 to 6%, depending on the author). What is usually found are slightly tendinous discrete structures that attach to the pubic tubercle. Because of this, Skandalakis, et al proposed to change the name to the "conjoined area".
Sources:
1. "Le Tendon Conjoint: Memoire realise dans le cadre du certificat d'anatomie, d'imagerie et de morphogenese" Leroux, H. Universite D' Nantes, 2005
2. "Hernia; Surgical Anatomy and Techniques" Skandalakis, J. et al. 1989 McGraw Hill
3. "Tratado de Anatomia Humana" Testut et Latarjet 8 Ed. 1931 Salvat Editores, Spain