Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Andreas Vesalius Bruxellensis (1514- 1564)

A Flemish anatomist and surgeon, Andreas Vesalius was born on December 31, 1514 in Brussels, Belgium. He is considered to be the father of the science of Anatomy. Up until his studies and publications human anatomy studies consisted only on the confirmation of the old doctrines of Galen of Pergamon (129AD - 200AD). Anatomy professors would read to the students from Galen's work and a demonstrator would point in a body to the area being described, if a body was used at all. The reasoning was that there was no need to dissect since all that was needed to know was already written in Galen's books. Vesalius, Fallopius, and others started the change by describing what they actually saw in a dissection as opposed to what was supposed to be there. 

Vesalius had a notorious career, both as an anatomist and as a surgeon. His revolutionary book "De Humani Corporis Fabrica: Libri Septem" was published in May 26, 1543. One of the most famous anatomical images is his plate 22 of the book, called sometimes "The Hamlet". You can see this image if you hover over Vesalius' only known portrait which accompanies this article. Sir William Osler said of this book "... it is the greatest book ever printed, from which modern medicine dates" 

After the original 1543 printing, the Fabrica was reprinted in 1555. It was re-reprinted and translated in many languages, although many of these printings were low-quality copies with no respect for copyright or authorship.

The story of the wood blocks with the carved images used for the original printing extends into the 20th century. In 1934 these original wood blocks were used to print 617 copies of the book "Iconaes Anatomica". This book is rare and no more can be printed because, sadly, during a 1943 WWII bombing raid over Munich all the wood blocks were burnt.

One interesting aspect of the book was the landscape panorama in some of his most famous woodcuts which was only "discovered" until 1903.

Vesalius was controversial in life and he still is in death. We know that he died on his way back from a pilgrimage to Jerusalem, but how he died, and exactly where he died is lost in controversy. We do know he was alive when he set foot on the port of Zakynthos in the island of the same name in Greece. He is said to have suddenly collapsed and die at the gates of the city, presumably as a consequence of scurvy. Records show that he was interred in the cemetery of the Church of Santa Maria delle Grazie, but the city and the church were destroyed by an earthquake and Vesalius' grave lost to history. Modern researchers are looking into finding the lost grave and have identified the location of the cemetery. This story has not ended yet.

For a detailed biography of Andreas Vesalius CLICK HERE.

Personal note: To commemorate Andrea Vesalius' 500th birthday in 2014, there were many scientific meetings throughout the world, one of them was the "Vesalius Continuum" anatomical meeting on the island of Zakynthos, Greece on September 4-8, 2014. This is the island where Vesalius died in 1564. I had the opportunity to attend and there are several articles in this website on the presence of Andreas Vesalius on Zakynthos island. During 2015 I also attended a symposium on "Vesalius and the Invention of the Modern Body" at the St. Louis University. At this symposium I had the honor of meeting of Drs. Garrison and Hast, authors of the "New Fabrica". Dr. Miranda


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Salomon Hakim, MD

This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.

Salomon Hakim, MD
Click for a larger image

Dr. Salomón Hakim (1922 - 2011). Dr. Hakim was born in the city of Barranquilla, Colombia. He started medical school in 1944 and elected neurosurgery as his specialty. He had special interest in electricity and physics, which he used extensively in his research.

In 1957 Dr. Hakim was exposed to a strange case of a young man with what was known then as "symptomatic occult hydrocephalus". Until that time the accepted knowledge was that hydrocephalus was due to an increase in intracranial pressure of different etiology. The problem was that the young man had normal pressure, yet had a hydrocephalus and enlarged ventricles. Dr. Hakim applied his knowledge of physics and laid the conceptual basis for what became known as "Normal Pressure Hydrocephalus" a condition until then unrecognized and that is found in aging patients with dementia, Alzheimer's, and other pathologies.

Working at home, Dr. Hakim developed a pressure-regulating shunt  to drain the excess cerebrospinal fluid (CSF) from the ventricular system of the brain. These valves were later produced by medical industry. His son Carlos has continued his legacy and now the Hakim programmable valve is one of the best CSF shunt systems in the world.

I had the pleasure of meeting Dr. Hakim in 1993 in Santiago, Chile, and again later in the US, as he presented his valve system to a group of neurosurgeons.  This short article does not do justice to the physician, researcher, and family man. I encourage you to read more in the following links. Dr. Miranda

Sources:
1. "Salomon Hakim and the Discovery of Normal-Pressure Hydrocephalus"Wallenstein, MB; McKhann, GM. Neurosurgery (2010) 67;1:155-159
2. "The Reprieve: Reversing Dementia"online article by Rose Tibayan
3. "Salomon Hakim, alma y vida de cient?fico"Article by Paulina Ortiz
4. 
"Salomon Hakim: Un milagro de Colombia para el mundo"
Original image courtesy of The Hydrocephalus Association


Lapar-

Abdominal regions - Modified from the original Davis, 1910 
Click for a larger image

The root term [-lapar-] term is Greex, and although today we use it to mean "abdomen", it actually means "flank" or "loins".

In its pure etymological meaning the root term [lapar], as in "laparotomy" or "laparoscopy" should be used to denote a surgical action in only two of the abdominal regions, the right and left lumbar regions (or flank regions) denoted in the accompanying image.

The first use of the term [-lapar-] referring to the whole of the abdominal region was in January, 1878 by Thomas Bryant, FRCS in his book "A Manual for the Practice of Surgery" using the term [laparotomy] to describe an "incision in the abdomen". Other terms used to denote the abdominal region are "ventral", and of course, "abdominal".

  • Laparotomy: the suffix [-otomy] means to "open" or "to cut", the term means then " to cut of to open the abdomen"
  • Laparoscope: an instrument used to view into the abdomen
  • Laparoscopy: the act of using a laparoscope
  • Laparostomy: an unusual procedure where the abdomen is not closed, but left partially open (but protected) so that the surgeon can come back periodically to perform an abdominal "lavage" to manage an intractable abdominal sepsis
  • Laparorrhaphy: the suffix [-orrhaphy] means "to repair". Refers to the repair or closure of a laparotomy

Sources:
1. Mughal, M. M., Bancewicz, J. and Irving, M. H. (1986), ‘Laparostomy’: A technique for the management of intractable intra-abdominal sepsis. Br J Surg, 73: 253–259
2. Thomas, B.(1878). "A Manual for the Practice of Surgery" PHiladelphia: Henry C. Lea and Sons


Cribriform

Ethmoid bone, superior view, showing the cribriform plate (www.bartleby.com)
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The etymology of this word arises from two Latin words; [cribrum], meaning "a sieve" and [forma], meaning "shape" or "shaped-like". The word [cribriform] means then "sieve-like" or "perforated with a large number or holes".

There are places in the body where the term applies. Examples are the cribriform plate (lamina cribrosa), a sieve-like region found in the superior aspect of the ethmoid bone (see accompanying image) , described in detail by Gabrielle Fallopius.  The olfactory nerves, extensions of the olfactory, bulb pass through the cribriform plate on their way to the olfactory epithelium, an area of the mucosa in the superior aspect of the nose. Another is the cribriform fascia (Hesselbach's fascia) on the anterosuperior aspect of the thigh through which passes the greater saphenous vein and other structures.

For more information on the ethmoid bone click here 

Source:
1. "Anatomy of the Human Body" Henry Gray 1918. Philadelphia: Lea & Febiger
2 "Tratado de Anatomia Humana" Testut et Latarjet 8 Ed. 1931 Salvat Editores, Spain
Original image in the public domain, by Henry VanDyke Carter, MD,  courtesy of bartleby.com 


Vein

From the Latin [vena], meaning "vein". Some early authors postulated that the term derivates from the Latin word [venio] meaning "to come", because the blood in the veins "comes in" to the heart. There are two root terms meaning "vein", the first is the Latin derivated [-ven-], as in the terms venous and intravenous. The second root term is Greek [-phleb-], as in the terms phlebectomy, phlebotomy, and phlebotomist. Peripheral veins have internal one-way valves, while most of the central veins (in the trunk) do not present with valves. Failure of a peripheral venous valve can lead to dilation of the vein, condition called a varix.

  • Venous: pertaining to a vein
  • Intravenous: inside or within a vein
  • Phlebectomy: removal of a vein
  • Phlebotomy: to open a vein

Carotid

Right carotid artery system - anterior view
Click for a larger image

The term [carotid] is Greek and means "to sleep", "to stupefy", or "to put to sleep". This arises from the observed fact that compression of the large arteries in the neck caused animals to fall asleep (Rufus of Ephesus c.100BC). Andrea Vesalius proposed the name "soporalis arteriae", but the Greek term [carotid] is what we use today. 

The carotid arterial system is bilateral. On the right side, the right common carotid artery arises from the brachiocephalic trunk, while on the left side the left common carotid artery arises from the aortic arch. The common carotid artery divides into an external and an internal carotid artery. The internal carotid artery presents a dilation close to its origin, the carotid sinus, and then heads superiorly to enter the carotid canal of the temporal bone. The internal carotid artery does not give any branches in the neck region and ends providing important branches to the eye and the arterial circle of Willis, which supplies part of the brain.

The external carotid ends giving origin to two arteries, the superficial temporal artery and the maxillary artery. The external carotid artery gives off six named branches:

• Superior thyroid artery
• Lingual artery
• Facial  artery
• Ascending pharyngeal artery
• Occipital artery
• Posterior auricular artery

Sources:
1. "The ancient Hellenic and Hippocratic origins of head and brain terminology" Panourias IG, et al Clin Anat 2012 Jul;25(5):548-581
2. "The origin of Medical Terms" Skinner, AH, 1970
Images property of: CAA.Inc. Artist: Dr. E. Miranda


Wilhelm Konrad Roentgen

This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.

Wilhem-Conrad Roentgen
Prof. Wilhem-Conrad Roentgen

Wilhelm Konrad Roentgen (1845 - 1923). A German physicist, Professor Roentgen started studying Physics at the University of Ultrech, and receiving his degree from the University of Zurich. Having observed fluorescence on a paper covered with barium platinocyanide close to an active cathode ray. Suspecting the presence of "invisible rays", he devised an experiment to prove this. 

On November 8, 1895 he confirmed his theory and called these invisible-to-the-eye emissions "X"-rays. He also observed the action of these "X"-rays on photographic plates, and that these rays could traverse through the human body, showing the bones. In fact, the first "roentgenogram" was an image of his wife's hand. If you hover over Professor Roentgen's image, you will see an depiction of this historic image. This image marks the beginning of the science of Radiology.

Professor Wilhelm Konrad Roentgen received many awards, medals, and recognitions. In 1901 he was awarded the Physics Nobel Prize.

Sources:
1. http://www.nobelprize.org

2. "The origin of Medical Terms" Skinner, HA; 1970

Both original images (1) and (2) are in the public domain and courtesy of the National Library of Medicine.
Thanks to Megan Ohse for suggesting this article