Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Andreas Vesalius Bruxellensis (1514- 1564)

A Flemish anatomist and surgeon, Andreas Vesalius was born on December 31, 1514 in Brussels, Belgium. He is considered to be the father of the science of Anatomy. Up until his studies and publications human anatomy studies consisted only on the confirmation of the old doctrines of Galen of Pergamon (129AD - 200AD). Anatomy professors would read to the students from Galen's work and a demonstrator would point in a body to the area being described, if a body was used at all. The reasoning was that there was no need to dissect since all that was needed to know was already written in Galen's books. Vesalius, Fallopius, and others started the change by describing what they actually saw in a dissection as opposed to what was supposed to be there. 

Vesalius had a notorious career, both as an anatomist and as a surgeon. His revolutionary book "De Humani Corporis Fabrica: Libri Septem" was published in May 26, 1543. One of the most famous anatomical images is his plate 22 of the book, called sometimes "The Hamlet". You can see this image if you hover over Vesalius' only known portrait which accompanies this article. Sir William Osler said of this book "... it is the greatest book ever printed, from which modern medicine dates" 

After the original 1543 printing, the Fabrica was reprinted in 1555. It was re-reprinted and translated in many languages, although many of these printings were low-quality copies with no respect for copyright or authorship.

The story of the wood blocks with the carved images used for the original printing extends into the 20th century. In 1934 these original wood blocks were used to print 617 copies of the book "Iconaes Anatomica". This book is rare and no more can be printed because, sadly, during a 1943 WWII bombing raid over Munich all the wood blocks were burnt.

One interesting aspect of the book was the landscape panorama in some of his most famous woodcuts which was only "discovered" until 1903.

Vesalius was controversial in life and he still is in death. We know that he died on his way back from a pilgrimage to Jerusalem, but how he died, and exactly where he died is lost in controversy. We do know he was alive when he set foot on the port of Zakynthos in the island of the same name in Greece. He is said to have suddenly collapsed and die at the gates of the city, presumably as a consequence of scurvy. Records show that he was interred in the cemetery of the Church of Santa Maria delle Grazie, but the city and the church were destroyed by an earthquake and Vesalius' grave lost to history. Modern researchers are looking into finding the lost grave and have identified the location of the cemetery. This story has not ended yet.

For a detailed biography of Andreas Vesalius CLICK HERE.

Personal note: To commemorate Andrea Vesalius' 500th birthday in 2014, there were many scientific meetings throughout the world, one of them was the "Vesalius Continuum" anatomical meeting on the island of Zakynthos, Greece on September 4-8, 2014. This is the island where Vesalius died in 1564. I had the opportunity to attend and there are several articles in this website on the presence of Andreas Vesalius on Zakynthos island. During 2015 I also attended a symposium on "Vesalius and the Invention of the Modern Body" at the St. Louis University. At this symposium I had the honor of meeting of Drs. Garrison and Hast, authors of the "New Fabrica". Dr. Miranda


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Interstices / interstitial

The word [interstice] is a derivation of the Latin term [interstitium] meaning "interval" or "spaces between". The plural form is [interstices]. The terms is used in anatomy to denote small spaces within a structure. As an example, bone marrow and venous sinuses are found in the [interstices] of the cancellous bone in the body of a vertebra.

The term is also used to describe different pathologies such as insterstitial cystitis and instertitial lung disease.

Word suggested by:Sara Mueller


Parietal

Lateral view of the skull
Click for a larger image

The word [parietal] has its origin in the Greek term [paries] meaning "wall". [Parietal] then means "pertaining to a wall", wall-related", or simply stated, "wall". Following are some examples of the use of this term.

The parietal bones of the cranium (os parietale), create the lateral "wall" of the cranium. These quadrangular bones join in the midline forming the sagittal suture. (see image). Click here for a detailed description of the parietal bone.

The term [parietal] is also used to denote membranes that are related to the body wall. The parietal peritoneum is the portion of the peritoneal membrane that is found away from the viscera and in relation to the abdominal wall.

The pleura is a membrane that lines the lungs, and it has a component that is related to the wall of the thorax. This is the [parietal] pleura.

There is a couple of cases where the use of term [parietal] is not related to a wall, but rather as "away from a viscus". An example of this would be the parietal pericardium, where the parietal component is the membrane that is away from the visceralpericardium.

An interesting use of the term is legal, where a [parietal] law, is used to denote a law that establishes boundaries or "walls" between legal parties.

Original image and links courtesy of bartleby.com


Diagnosis / Prognosis

These two terms are related by the Greek root term [-gnos-] which means "knowledge".

The first word [diagnosis] has the prefix [dia-] meaning "apart" or "to take apart". [Diagnosis] then means "to discern", or in a more detailed explanation, it is "knowledge by taking apart", identifying a pathology by looking at all its components.

The second word [prognosis] has the prefix [pro-] meaning "forward". Prognosis is then "forward knowledge", an statement of outcome of the course of a pathology.

Words suggested by:Sara Mueller


Coronary arteries

Coronary Arteries
Click for a larger image

The term [coronary] comes from the Latin root [corona] meaning "crown", therefore [coronary] is used to denote a structure that surrounds another as a crown or a garland. In the heart, the coronary arteries and their branches form a crown that surrounds the heart at the level of the atrioventricular sulcus. There are two coronary arteries, the right coronary artery (RCA), and the left coronary artery (*). Both these coronary arteries are the only branches that arise from the ascending aorta.

The right coronary artery passes from the anterior to the posterior surface of the heart, ending in a terminal branch, the posterior descending artery, or PDA. The left coronary artery, sometimes called the "left main", gives origin to two branches: the circumflex artery (CFX) and the left anterior descending artery (LAD). Each one of these arteries gives origin to several named branches. 

There can be interesting anatomical variations in the coronary arteries of the heart. Heart and coronary artery anatomy is one of the topics developed and delivered by CAA, Inc.

Image property of: CAA.Inc..  Artist: Victoria G. Ratcliffe


Ventricle

Heart model - LAO cranial view
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The Latin word [ventriculus] means "little sac" or "little belly" and arises from the Latin term [venter] meaning "belly" or "abdomen". Originally the term [ventricle] was used to denote the stomach. This use of the word has changed and now the term [ventricle] denotes a "sac" or "cavity", as in the "ventricles of the brain". The term [ventricular] means "pertaining or related to a ventricle".

In the case of the heart, the ventricles represent the two inferior chambers of the heart. (see image, items "C=right ventricle" and "D=left ventricle"). The anatomy of the right and left ventricles is quite different. The left ventricle has a thicker lateral muscular wall, almost three times thicker than the lateral wall of the right ventricle.

Image property of:CAA.Inc.Photographer:D.M. Klein


Perineum

Perineum, inferior view
Click for a larger image

The term [perineum] has two definitions:

1. It is the area of the trunk inferior to the pelvic diaphragm. As such, the perineum contains the ischioanal fossa, the urogenital diaphragm, and the superficial genitalia.

2. It is the area of the body between the upper thighs containing the external openings of urethra, vagina, and anus. This area is delimited (see image) by the symphysis pubis, ischial tuberosities, and coccyx.

The perineum, as described in the second definition, is formed by two large triangular regions. The anterior region (in purple) is called the urogenital triangle, and the posterior region (in yellow) is called the anal triangle. 

There is another definition in use that is wrong! Please understand that I post it here as an example only. "The perineum is the area that is found between the scrotum (or vagina) anteriorly and the anus posteriorly". This is NOT the definition of perineum, it is the definition or location of the perineal body, the center of the pelvic floor where 17 named muscles attach of cross. The muscles are:

  • Iliococcygeus (2)
  • Pubococcygeus (2)
  • Superficial transverse perineal (2)
  • Deep transverse perineal (2)
  • Puborectalis (2)
  • Bulbospongiosus (2)
  • Pubovaginalis (2)
  • Sphincter urethae (1)

Image property of: CAA.Inc.. Artist: D.M. Klein.
Word suggested and edited by:Dr. Sanford S. Osher, MTD Contributor