Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.
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Georg Eduard Von Rindfleisch
(1836 – 1908)
German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.
He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.
After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.
Associated eponyms
"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.
"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.
Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.
Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999) Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross
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These two opposite terms must be studied together. Both words are used as directional anatomical and surgical terms, and most importantly, they are relationship terms, that is, they express the spatial location of one structure in reference to another.
The term [anterior] is Latin and means "in front of". It is related to the prefix [ante-] which means "before", or "anterior" and the Latin [anticus], which means "in the very front".
The term [posterior] is more complex. Although it is based on a Latin term meaning "after", the prefix [poster-] is used as a comparative to mean "behind (a structure of reference)". Following are some examples of the proper use of these terms:
- The aorta is anterior to the spine
- The sternum is anterior to the heart
- The occipital bone is the most posterior bone of the cranium
- The trachea is anterior to the esophagus
Because a human body is always studied in the anatomical position, in the hand, the anterior aspect is the palm and in this case a synonym for anterior is [volar].
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This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.
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Dr. Salomón Hakim (1922 - 2011). Dr. Hakim was born in the city of Barranquilla, Colombia. He started medical school in 1944 and elected neurosurgery as his specialty. He had special interest in electricity and physics, which he used extensively in his research.
In 1957 Dr. Hakim was exposed to a strange case of a young man with what was known then as "symptomatic occult hydrocephalus". Until that time the accepted knowledge was that hydrocephalus was due to an increase in intracranial pressure of different etiology. The problem was that the young man had normal pressure, yet had a hydrocephalus and enlarged ventricles. Dr. Hakim applied his knowledge of physics and laid the conceptual basis for what became known as "Normal Pressure Hydrocephalus" a condition until then unrecognized and that is found in aging patients with dementia, Alzheimer's, and other pathologies.
Working at home, Dr. Hakim developed a pressure-regulating shunt to drain the excess cerebrospinal fluid (CSF) from the ventricular system of the brain. These valves were later produced by medical industry. His son Carlos has continued his legacy and now the Hakim programmable valve is one of the best CSF shunt systems in the world.
I had the pleasure of meeting Dr. Hakim in 1993 in Santiago, Chile, and again later in the US, as he presented his valve system to a group of neurosurgeons. This short article does not do justice to the physician, researcher, and family man. I encourage you to read more in the following links. Dr. Miranda
Sources:
1. "Salomon Hakim and the Discovery of Normal-Pressure Hydrocephalus"Wallenstein, MB; McKhann, GM. Neurosurgery (2010) 67;1:155-159
2. "The Reprieve: Reversing Dementia"online article by Rose Tibayan
3. "Salomon Hakim, alma y vida de cient?fico"Article by Paulina Ortiz
4. "Salomon Hakim: Un milagro de Colombia para el mundo"
Original image courtesy of The Hydrocephalus Association
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The root term [-lapar-] term is Greex, and although today we use it to mean "abdomen", it actually means "flank" or "loins".
In its pure etymological meaning the root term [lapar], as in "laparotomy" or "laparoscopy" should be used to denote a surgical action in only two of the abdominal regions, the right and left lumbar regions (or flank regions) denoted in the accompanying image.
The first use of the term [-lapar-] referring to the whole of the abdominal region was in January, 1878 by Thomas Bryant, FRCS in his book "A Manual for the Practice of Surgery" using the term [laparotomy] to describe an "incision in the abdomen". Other terms used to denote the abdominal region are "ventral", and of course, "abdominal".
- Laparotomy: the suffix [-otomy] means to "open" or "to cut", the term means then " to cut of to open the abdomen"
- Laparoscope: an instrument used to view into the abdomen
- Laparoscopy: the act of using a laparoscope
- Laparostomy: an unusual procedure where the abdomen is not closed, but left partially open (but protected) so that the surgeon can come back periodically to perform an abdominal "lavage" to manage an intractable abdominal sepsis
- Laparorrhaphy: the suffix [-orrhaphy] means "to repair". Refers to the repair or closure of a laparotomy
Sources:
1. Mughal, M. M., Bancewicz, J. and Irving, M. H. (1986), ‘Laparostomy’: A technique for the management of intractable intra-abdominal sepsis. Br J Surg, 73: 253–259
2. Thomas, B.(1878). "A Manual for the Practice of Surgery" PHiladelphia: Henry C. Lea and Sons
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The etymology of this word arises from two Latin words; [cribrum], meaning "a sieve" and [forma], meaning "shape" or "shaped-like". The word [cribriform] means then "sieve-like" or "perforated with a large number or holes".
There are places in the body where the term applies. Examples are the cribriform plate (lamina cribrosa), a sieve-like region found in the superior aspect of the ethmoid bone (see accompanying image) , described in detail by Gabrielle Fallopius. The olfactory nerves, extensions of the olfactory, bulb pass through the cribriform plate on their way to the olfactory epithelium, an area of the mucosa in the superior aspect of the nose. Another is the cribriform fascia (Hesselbach's fascia) on the anterosuperior aspect of the thigh through which passes the greater saphenous vein and other structures.
For more information on the ethmoid bone click here
Source:
1. "Anatomy of the Human Body" Henry Gray 1918. Philadelphia: Lea & Febiger
2 "Tratado de Anatomia Humana" Testut et Latarjet 8 Ed. 1931 Salvat Editores, Spain
Original image in the public domain, by Henry VanDyke Carter, MD, courtesy of bartleby.com
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From the Latin [vena], meaning "vein". Some early authors postulated that the term derivates from the Latin word [venio] meaning "to come", because the blood in the veins "comes in" to the heart. There are two root terms meaning "vein", the first is the Latin derivated [-ven-], as in the terms venous and intravenous. The second root term is Greek [-phleb-], as in the terms phlebectomy, phlebotomy, and phlebotomist. Peripheral veins have internal one-way valves, while most of the central veins (in the trunk) do not present with valves. Failure of a peripheral venous valve can lead to dilation of the vein, condition called a varix.
- Venous: pertaining to a vein
- Intravenous: inside or within a vein
- Phlebectomy: removal of a vein
- Phlebotomy: to open a vein
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The term [carotid] is Greek and means "to sleep", "to stupefy", or "to put to sleep". This arises from the observed fact that compression of the large arteries in the neck caused animals to fall asleep (Rufus of Ephesus c.100BC). Andrea Vesalius proposed the name "soporalis arteriae", but the Greek term [carotid] is what we use today.
The carotid arterial system is bilateral. On the right side, the right common carotid artery arises from the brachiocephalic trunk, while on the left side the left common carotid artery arises from the aortic arch. The common carotid artery divides into an external and an internal carotid artery. The internal carotid artery presents a dilation close to its origin, the carotid sinus, and then heads superiorly to enter the carotid canal of the temporal bone. The internal carotid artery does not give any branches in the neck region and ends providing important branches to the eye and the arterial circle of Willis, which supplies part of the brain.
The external carotid ends giving origin to two arteries, the superficial temporal artery and the maxillary artery. The external carotid artery gives off six named branches:
• Superior thyroid artery
• Lingual artery
• Facial artery
• Ascending pharyngeal artery
• Occipital artery
• Posterior auricular artery
Sources:
1. "The ancient Hellenic and Hippocratic origins of head and brain terminology" Panourias IG, et al Clin Anat 2012 Jul;25(5):548-581
2. "The origin of Medical Terms" Skinner, AH, 1970
Images property of: CAA.Inc. Artist: Dr. E. Miranda