Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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-nym-

Although not a medical root term, the root [-nym-] arises from the Greek [onoma] meaning "name". There are many terms that incorporate this root:

  • Eponym: Use of a proper name to denote a structure
  • Eunym: [Eu-] is a prefix that means "good", so it imeans a "good name". Also written as "euonym"
  • Homonym: Same name
  • Synomym: "A name with the same sense, or same meaning"
  • Antomym: From the Greek [ant- and anti] meaning opposite. An opposite name
  • Anonym: From the Greek [an- and ano-] meaning "without". Without a name (anonymous)
  • Pseudonym: From the Greek [Pseudo-] meaning "false". A false name
  • Toponym: From [topos], meaning place. The name of a place or location

Henry Koplik, MD

This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.

Henry Koplik, MD
Henry Koplik, MD

Henry Koplik, MD (1858 -1927). American pediatrician and researcher, was born in 1858 in the city of New York.  He received his MD from the College of Physicians and Surgeons at the Colombia University in New York. He spent several years studying in Berlin, Vienna, and Prague. Upon his return to the US he worked at the lower Manhattan Good Samaritan dispensary, where he later built a large pediatric outpatient clinic which became a model for the care of infants and children. In fact, under Dr Koplik's direction, this clinic became the world's first "milk depot" providing fresh milk and infant food for underprivileged mothers in the area. Dr. Koplik was one of the founders of the American Pediatric Society, and was one of its presidents.

Mostly remembered by the pathognomonic and eponymic "Koplik's spots", Dr Koplik had many other achievements. Some of them include the prophylaxis of a milk depot, the strict discipline in diagnosis and care of the pediatric patient,  the discovery of the bacillus responsible for whooping cough, the prevention of cross-contamination at a pediatric ward, etc.

Dr. Koplik wrote a number of clinical and research papers on hygiene and public health, as well on a number of medical topics, plus a book on "Diseases of Infancy and Childhood". 

Sources:
1. "Koplik's Spots for the Record: an Illustrated Historical Note" Brem, J; Clin Ped 1972 11:3 161-163
2. "Pediatric Profiles: Henry Koplik (1858-1927)" Bass, MH J Ped 1957 119-125
3. "The History of the First Milk Depot or Gouttes de Lait With Consultations in America" JAMA 50: 1574, 1914.
4. "Some Pediatric Eponyms: Koplik's Spots," W. R. Bett Brit. J. Child.Dis. 28: 127, 1931 
Original image in the public domain, courtesy of the National Institutes of Health.


Aortic arch

Aortic arch and branches
Click for a larger image

The aortic arch is a segment of the aorta that arches from the midline towards posterior and to the left. It presents with three branches. From proximal to distal they are the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery. There are several anatomical variations of the branches of the aortic arch.

There is no clear anatomical landmark to denote the ending of the ascending aorta and the beginning of the aortic arch, as there is no clear anatomical landmark to denote the ending of the aortic arch and the beginning of the descending aorta. Anatomists use as a reference a horizontal plane that passes through the angle of Louis. Since this plane also separates the inferior from the superior mediastinum, the aortic arch is found in the superior mediastinum, while the ascending and descending aorta are found in the inferior mediastinum.

The aortic arch has anatomical relations with the bifurcation of the trachea, the pulmonary trunk and its bifurcation, and the left brachiocephalic vein. In its inferior surface, the aortic arch in the adult has the embryological remnant of the ductus arteriousus, called the ligamentum arteriosum.

The term "aortic arch" was coined and first used by Lorenz Heister (1683 1785) 

Image property of: CAA.Inc.Artist: Victoria G. Ratcliffe


-angi-

This is a medical root term that originates from the Greek and means "vessel", as in a "container". The term is commonly misunderstood to mean "artery". The original meanings of the term in early Greek and Roman medicine where multiple. It was Lorenz Heister (1683-1758) who first used the term in its modern meaning. Applications of this root term include:

  • Angiology: Study of vessels
  • Angioma: Vessel tumor or mass, usually referred to a malformation of knotted vessels. The plural form is "angiomata"
  • Angioplasty: Reshaping of a vessel
  • Angiitis: Inflammation of a vessel. Note the double "i" in the word. This is the correct form of the term. "Angitis" is not correct!
  • Angiogenesis: Creation or generation of vessels
  • Neoangiogenesis: The prefix [neo-] means [new], therefore the term means "creation or generation of new vessels"
  • Cholangiogram: The prefix [chol-] means "bile", while the suffix [-ogram] means "examination of". A [cholangiogram] is the "examination of a bile vessel"
  • Cineangiogram: The prefix [cine-] means "movement", although we use it to mean "movie", while the suffix [-ogram] means "examination of". A [cineangiogram] is the "examination of a vessel in movement"

-arthr-

This is a medical root term that originates from the Greek "arthron" which means "joint". The term is used in many medical words. Applications of this root term include:

  • Arthrotomy: Opening of a joint
  • Arthritis: Inflammation (or infection) of a joint
  • Arthrology: Study of a joint
  • Arthrodesis: Fixation of a joint
  • Arthropathy: A disease affecting a joint
  • Arthroplasty: Reshaping of a joint
  • Arthroscopy: Visualizing inside a joint with a scope

As a side note: What is the plural form for arthritis? Hover your cursor over the word to see the answer


Charles H. McBurney, MD

This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.

Charles H. McBurney, MD
Charles H. McBurney, MD

Charles H. McBurney, MD (1845- 1913). British surgeon and anatomist, Dr. McBurney studied at Harvard University, and received his MD from the Colombia University in New York. At the forefront of the aseptic technique revolution, Dr. MacBurney, following Halsted's example, required the use of surgical gloves and strict aseptic technique in his operating room, considered the "first modern operating room in America"

His studies focused on appendicitis, and demonstrated a point of maximum tenderness at a point "exactly between an inch and a half and two inches from the anterior spinous process of the ileum on a straight line drawn between that process and the umbilicus". This point has become known as the eponymic "McBurney's point". There is a discrepancy between the original description of this point by McBurney and some medical publications. Continuing his research on the surgical approach to the inflamed vermiform appendix, in 1894 Dr. MacBurney presented an approach that used a small incision for appendectomy. This incision is know today as "McBurney's incision."

Sources:
1. "Charles Heber McBurney (1845 – 1913)" Yale,SH and Musana, KA Clin Med Res. 2005 August; 3(3): 187–189.
2. "Charles McBurney (1845–1913)—point, sign, and incision"  JAMA 1966;197:1098–1099
3. "The first modern operating room in America"  Clemons BJ AORN J. 2000 Jan;71(1):164-8, 170
Original image in the public domain, courtesy of the National Institutes of Health