Sylviane Déderix. Ph.D.

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A Moment in History

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999) Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross

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Sylviane Déderix. Ph.D.

Published: Tuesday, May 03, 2016 07:00

Sylviane Déderix. Ph.D.

Dr. Sylviane Déderix is a Postdoctoral fellow at Catholic University of Louvain in the Aegean Interdisciplinary Studies Research Group. She has a Ph.D. in History, Art, and Archeology.

She is also a collaborator of the Laboratory of Geophysical- Satellite Remote Sensing & Archaeoenvironment and a member of the Sissi Archaeological Project (Crete, Greece) in charge of the architectural study of the house tombs excavated in the cemetery.

She has collaborated with the effort of finding the lost grave of Andreas Vesalius using satellite imagery and geophysical approaches to pinpoint the location of the cemetery of the Church of Santa Maria delle Grazie after the island of Zakynthos was practically destroyed by an earthquake in 1953.

Since then the island and its buildings have been rebuilt and streets relocated, which causes the cemetery to have been lost until her work was published. Now we know the approximate location of the cemetery close to the current intersection of the Kolokotroni and Kolyva streets, and further studies can be conducted.

Thanks to Dr. Déderix for collaborating with "Medical Terminology Daily" with the article "In Search of Andreas Vesalius, The Quest for the Lost Grave - The Sequel" which she co-authored with Pascale Pollier and Theo Dirix.

For more information on Dr. Déderix, click here. For her CV, click here.