Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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William T.G. Morton

This article is part of the series "A Moment in History" where we honor those who have contributed to the growth of medical knowledge in the areas of anatomy, medicine, surgery, and medical research.

William TG Morton
William T.G. Morton

William Thomas Green Morton  (1819-1868). American dentist, was born in Charlton, MA. In 1840, He started his studies at the Baltimore College of Dental Surgery. Interestingly, he left college without graduating to study with Horace Wells, DDS, in Hartford, CT. He started Medical school at Harvard, and left without graduating. In 1852 Morton received his honorary MD degree.

In 1846, Morton was able to successfully and painlessly extract a tooth from a patient under ether administration. To this effect he used an ether inhaler of his own invention that he called “Letheon”. This led to his now-famous demonstration of the use of ether as an anesthetic on October 16,1846 at the Massachusetts General Hospital first operating room, today known as the "Ether Dome". This is the first-ever recorded use of anesthesia as a way to reduce or eliminate pain in surgery, one of the revolutions in surgery, the other being Lister’s antiseptic technique.

Morton tried, unsuccessfully, to establish a patent on his discovery against Horace Wells (1815 – 1848). The litigation costs led him to poverty and he died with no money on 1868.

Although the American Dental Association in 1864 passed a formal resolution stating that Horace Wells was the discoverer of anesthesia, the name of William TG Morton has been tied to it since.

Sources
1. “William Thomas Green Morton (1819-1868” Keys. TE. Anesth and Analg (1973) 52: (2) 166
2. ” Morton, dentist, who first publicly demonstrated ether anesthesia; a short biography” Archer WH, William TG. J Am Dent Assoc. 1946 Dec 1;33(23):1528-32
3. “Horace Wells: Discoverer of Anesthesia” Jacobsohn PH. Anesth Prog (1995) 42:73-75
4. “The last days of William Thomas Green Morton” Vandam LD J Clin Anesth (1996) Sep;8(6):431-4334