Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Andreas Vesalius Bruxellensis (1514- 1564)

A Flemish anatomist and surgeon, Andreas Vesalius was born on December 31, 1514 in Brussels, Belgium. He is considered to be the father of the science of Anatomy. Up until his studies and publications human anatomy studies consisted only on the confirmation of the old doctrines of Galen of Pergamon (129AD - 200AD). Anatomy professors would read to the students from Galen's work and a demonstrator would point in a body to the area being described, if a body was used at all. The reasoning was that there was no need to dissect since all that was needed to know was already written in Galen's books. Vesalius, Fallopius, and others started the change by describing what they actually saw in a dissection as opposed to what was supposed to be there. 

Vesalius had a notorious career, both as an anatomist and as a surgeon. His revolutionary book "De Humani Corporis Fabrica: Libri Septem" was published in May 26, 1543. One of the most famous anatomical images is his plate 22 of the book, called sometimes "The Hamlet". You can see this image if you hover over Vesalius' only known portrait which accompanies this article. Sir William Osler said of this book "... it is the greatest book ever printed, from which modern medicine dates" 

After the original 1543 printing, the Fabrica was reprinted in 1555. It was re-reprinted and translated in many languages, although many of these printings were low-quality copies with no respect for copyright or authorship.

The story of the wood blocks with the carved images used for the original printing extends into the 20th century. In 1934 these original wood blocks were used to print 617 copies of the book "Iconaes Anatomica". This book is rare and no more can be printed because, sadly, during a 1943 WWII bombing raid over Munich all the wood blocks were burnt.

One interesting aspect of the book was the landscape panorama in some of his most famous woodcuts which was only "discovered" until 1903.

Vesalius was controversial in life and he still is in death. We know that he died on his way back from a pilgrimage to Jerusalem, but how he died, and exactly where he died is lost in controversy. We do know he was alive when he set foot on the port of Zakynthos in the island of the same name in Greece. He is said to have suddenly collapsed and die at the gates of the city, presumably as a consequence of scurvy. Records show that he was interred in the cemetery of the Church of Santa Maria delle Grazie, but the city and the church were destroyed by an earthquake and Vesalius' grave lost to history. Modern researchers are looking into finding the lost grave and have identified the location of the cemetery. This story has not ended yet.

For a detailed biography of Andreas Vesalius CLICK HERE.

Personal note: To commemorate Andrea Vesalius' 500th birthday in 2014, there were many scientific meetings throughout the world, one of them was the "Vesalius Continuum" anatomical meeting on the island of Zakynthos, Greece on September 4-8, 2014. This is the island where Vesalius died in 1564. I had the opportunity to attend and there are several articles in this website on the presence of Andreas Vesalius on Zakynthos island. During 2015 I also attended a symposium on "Vesalius and the Invention of the Modern Body" at the St. Louis University. At this symposium I had the honor of meeting of Drs. Garrison and Hast, authors of the "New Fabrica". Dr. Miranda


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The landscape panorama of Vesalius’ “Muscle Men” (1)

 Eight-series landscape panorama of Vesalius' muscle men plates. Paintings attributed to Jan Stephan Van Calcar

UPDATED: There is no doubt that the book “De Humani Corporis Fabrica Libri Septem” written by Andreas Vesalius and published by Johannes Oporinus in May, 1543 is one of the most important scientific anatomical and medical books ever written. Much has been said about the place this book has in medical history as part of the discarding of dogmas and the establishment of scientific observation and thinking.

Some of the most intriguing images published in the book are fourteen woodcuts in the second book. These amazing and detailed images show the muscles in a whole body as it is dissected. The text details the structures and the procedure of how the dissection is performed.

It is believed that these images were done by Jan Stephan Van Calcar, an artist from the Titian’s studio, although there are indications that these images may have been authored by somebody else, or even that they were the effort of more than one artist working under the close supervision of Andreas Vesalius.

Today’s anatomical images are very descriptive and the artistry is relegated to the technique used for the depiction of the image. In Vesalius’ muscle men plates each image has a background showing a landscape. It was not until 1903 that it was discovered that the landscapes of the different images were part of a complete landscape. This is evident if these images are placed side by side. There have been several books and articles published on these images. Interestingly, some of the images had to be reversed to be placed in the panorama. This is due to the process of cutting the woodblocks.

The image in this article is one of two identified and composed by Harvey Cushing in 1943 (see sources). He calls it the "eight-series". The "six-series" can be seen here. To see Cushing's original template click here. The panorama of the six-series was identified by Cushing to be an area of the Euganean hills near Venice and Padua, Italy. There landscape formed by the eight-series is an actual region near Padua, Italy showing the ruins of old Roman baths. Cavanagh (1938) adds more information on these images, for his .pdf article, click here.

The image shown at the top of this article was created using original images from Vesalius’ Fabrica and composed using Adobe Fireworks CS5. Click on the image for a larger depiction. The large image is 1800px wide.

NOTE: In June 2023, I was able to purchase a single leaf of the 1543 Fabrica, page 187, which depicts one of the "muscle men". In the panorama image in this article it is figure number 3, from left to right. For more information on this image click here. This image is now properly framed in my office. Dr. Miranda.

This article continues here: "The landscape panorama of Vesalius' Muscle Men (2)"

Sources:
1. “A New View of the Vesalian Landscape” Cavanagh,  GST Med Hist 1983, 27: 77-79
2. “The Panorama of Vesalius: A 'Lost' Design From Titian's Studio” Skandalakis, JE JAMA May 28, 1997, Vol 277, No. 20
3. “A Drawing for the Fabrica; and some Thoughts Upon the Vesalius Muscle-Men” Kemp. M. Med Hist. Jul 1970; 14(3): 277–288
4. “Andreas Vesalius: The Making, the Madman and the Myth” Joffe, SN. Persona Publishing 2009
5. "A Bio-Bibliography of Andreas Vesalius" Cushing, H. (1943) Schumann's