Medical Terminology Daily - Est. 2012

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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Spine- Lateral view
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UPDATED: In both these words the suffix [-osis] means "condition". The root term [-kyph-] is Greek and means "bent or bowed" without an indication of the direction of bending, thus the term was originally used for any abnormal spinal curvature. It was Hippocrates who first used this term to denote "hunchback". Since then the term [kyphosis] denotes a curvature of the spine towards posterior, or better described, a spinal curvature in the median plane with a posterior convexity.

Hippocrated also used the Greek term [lordosis] to denote a curvature opposite to kyphosis. Lordosis is then a spinal curvature in the median plane with an posterior concavity.

In the human spine, as viewed from the lateral aspect (see image), there are four normal curvatures. The cervical and lumbar curvatures are lordotic, while the thoracic and sacrococcygeal curvatures are kyphotic. Based on this description kyphosis and lordosis are normal conditions of the human spine.

A pathological, excessive, or exacerbated curvature should be denoted with the terms [hyperkyphosis] and [hyperlordosis] respectively; the prefix [hyper-] meaning "excessive". Through use, the terms [kyphosis] and [lordosis] are also used to denote pathological conditions. Hyperkyphosis has mostly a thoracic presentation, while hyperlordosis has mostly a lumbar presentation.

In vernacular  terms, an individual with hyperkyphosis is known as a "hunchback", while an individual with hyperlordosis is known as a "swayback".

Image property of: CAA.Inc. Artist:D.M. Klein