Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Andreas Vesalius Bruxellensis (1514- 1564)

A Flemish anatomist and surgeon, Andreas Vesalius was born on December 31, 1514 in Brussels, Belgium. He is considered to be the father of the science of Anatomy. Up until his studies and publications human anatomy studies consisted only on the confirmation of the old doctrines of Galen of Pergamon (129AD - 200AD). Anatomy professors would read to the students from Galen's work and a demonstrator would point in a body to the area being described, if a body was used at all. The reasoning was that there was no need to dissect since all that was needed to know was already written in Galen's books. Vesalius, Fallopius, and others started the change by describing what they actually saw in a dissection as opposed to what was supposed to be there. 

Vesalius had a notorious career, both as an anatomist and as a surgeon. His revolutionary book "De Humani Corporis Fabrica: Libri Septem" was published in May 26, 1543. One of the most famous anatomical images is his plate 22 of the book, called sometimes "The Hamlet". You can see this image if you hover over Vesalius' only known portrait which accompanies this article. Sir William Osler said of this book "... it is the greatest book ever printed, from which modern medicine dates" 

After the original 1543 printing, the Fabrica was reprinted in 1555. It was re-reprinted and translated in many languages, although many of these printings were low-quality copies with no respect for copyright or authorship.

The story of the wood blocks with the carved images used for the original printing extends into the 20th century. In 1934 these original wood blocks were used to print 617 copies of the book "Iconaes Anatomica". This book is rare and no more can be printed because, sadly, during a 1943 WWII bombing raid over Munich all the wood blocks were burnt.

One interesting aspect of the book was the landscape panorama in some of his most famous woodcuts which was only "discovered" until 1903.

Vesalius was controversial in life and he still is in death. We know that he died on his way back from a pilgrimage to Jerusalem, but how he died, and exactly where he died is lost in controversy. We do know he was alive when he set foot on the port of Zakynthos in the island of the same name in Greece. He is said to have suddenly collapsed and die at the gates of the city, presumably as a consequence of scurvy. Records show that he was interred in the cemetery of the Church of Santa Maria delle Grazie, but the city and the church were destroyed by an earthquake and Vesalius' grave lost to history. Modern researchers are looking into finding the lost grave and have identified the location of the cemetery. This story has not ended yet.

For a detailed biography of Andreas Vesalius CLICK HERE.

Personal note: To commemorate Andrea Vesalius' 500th birthday in 2014, there were many scientific meetings throughout the world, one of them was the "Vesalius Continuum" anatomical meeting on the island of Zakynthos, Greece on September 4-8, 2014. This is the island where Vesalius died in 1564. I had the opportunity to attend and there are several articles in this website on the presence of Andreas Vesalius on Zakynthos island. During 2015 I also attended a symposium on "Vesalius and the Invention of the Modern Body" at the St. Louis University. At this symposium I had the honor of meeting of Drs. Garrison and Hast, authors of the "New Fabrica". Dr. Miranda


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“The King’s Anatomist” – The Journey of Andreas Vesalius

The King's Anatomist - Book by Ron Blumenfeld MD
The King's Anatomist - Book Cover
Click on the image for a larger version

[UPDATED 11/30/2023] “In 1565 Brussels, the reclusive mathematician Jan van den Bossche receives shattering news that his lifelong friend, the renowned and controversial anatomist Andreas Vesalius, has died on the Greek island of Zante (today’s Zakynthos) returning from a pilgrimage to the Holy Land. Jan decides to journey to his friend’s grave to offer his last goodbye…” Thus begins the saga and the book the “King’s Anatomist”.

In June 2022 during the annual American Association of Clinical Anatomists (AACA) meeting in Fort Worth, TX, I was lucky to bid and win this, one of the latest books on Andreas Vesalius. This book, written by Ron Blumenfeld, MD. proved to be not only a great read, but also an quite historically accurate story. Let me explain this statement.

The book belongs to the genre of Historical Fiction, where the author does detailed research on a topic and then writes on accurate background but adds fictional characters and situations. Sometimes, as in this book, it follows a mystery that slowly unravels leading to shocking situations. To be fair, the author does explain what is not necessarily quite historically accurate, so as to leave no doubt about what is real or not.

The book is enthralling, the plot well developed, and the description of the academic environment, the details of the scenery for the travelers, the pettiness of war, etc., is not only interesting, but also portrays the times during the life of Andreas Vesalius in such a way that I felt transported there. It was very difficult to put the book down until I finished it.

The author does a great job getting us a little bit closer to who was Andreas Vesalius, the child at school, the youngster, the anatomist, the friend, the father, and the husband.

I should probably stop here and let you decide on the book for yourself without giving too much away. I strongly recommend this book and hope that you will enjoy it as much as I did. You can visit Ron’s website here to buy his book.

Ron and I both attended the 2014 “Vesalius Continuum” meeting in the Greek island of Zakynthos. This meeting celebrated the 500th anniversary of the birth of Andreas Vesalius. Part of the book he wrote is based on the discussions and presentations at this meeting.

Ron Blumenfeld and me in Antwerp
Ron Blumenfeld

Following are some excerpts of Ron’s bio and website in his own words:

“I’m a native New Yorker, pediatrician and health care executive who reunited with his inner writer in retirement. I surrendered the pleasure of writing columns on various topics for my local newspaper in Connecticut to focus on my debut novel, The King’s Anatomist”

“There always was a writer cooped up inside me, but he got loose only after I retired. I had permitted him to show up only in school classes, health and business writing, and newspaper columns, but I realize now that I kept him on a short leash because I was afraid of him – afraid of his disruptive potential and afraid of what he would look like to the world. But at this point in my life, I got past those excuses and let him out to see what he could do.

"The King’s Anatomist, it turned out, was an ideal writing project, anchored in facts, but with ample room for creativity. Thank you, Andreas Vesalius, for being such an interesting guy.”

UPDATE: I was glad to see Ron Blumenfeld again when he attended the 2023 Vesalius Triennial Meeting in the city of Antwerp, Belgium where I had been invited to participate. We had a great time in the conference, walking around the city, and at local restaurants! Also, thank you, Ron, for signing and dedicating my personal copy of your book. It has a nice place in my library. Dr. Miranda.

Should you want to look for more information on Andreas Vesalius in this website click here.