Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Andreas Vesalius Bruxellensis (1514- 1564)

A Flemish anatomist and surgeon, Andreas Vesalius was born on December 31, 1514 in Brussels, Belgium. He is considered to be the father of the science of Anatomy. Up until his studies and publications human anatomy studies consisted only on the confirmation of the old doctrines of Galen of Pergamon (129AD - 200AD). Anatomy professors would read to the students from Galen's work and a demonstrator would point in a body to the area being described, if a body was used at all. The reasoning was that there was no need to dissect since all that was needed to know was already written in Galen's books. Vesalius, Fallopius, and others started the change by describing what they actually saw in a dissection as opposed to what was supposed to be there. 

Vesalius had a notorious career, both as an anatomist and as a surgeon. His revolutionary book "De Humani Corporis Fabrica: Libri Septem" was published in May 26, 1543. One of the most famous anatomical images is his plate 22 of the book, called sometimes "The Hamlet". You can see this image if you hover over Vesalius' only known portrait which accompanies this article. Sir William Osler said of this book "... it is the greatest book ever printed, from which modern medicine dates" 

After the original 1543 printing, the Fabrica was reprinted in 1555. It was re-reprinted and translated in many languages, although many of these printings were low-quality copies with no respect for copyright or authorship.

The story of the wood blocks with the carved images used for the original printing extends into the 20th century. In 1934 these original wood blocks were used to print 617 copies of the book "Iconaes Anatomica". This book is rare and no more can be printed because, sadly, during a 1943 WWII bombing raid over Munich all the wood blocks were burnt.

One interesting aspect of the book was the landscape panorama in some of his most famous woodcuts which was only "discovered" until 1903.

Vesalius was controversial in life and he still is in death. We know that he died on his way back from a pilgrimage to Jerusalem, but how he died, and exactly where he died is lost in controversy. We do know he was alive when he set foot on the port of Zakynthos in the island of the same name in Greece. He is said to have suddenly collapsed and die at the gates of the city, presumably as a consequence of scurvy. Records show that he was interred in the cemetery of the Church of Santa Maria delle Grazie, but the city and the church were destroyed by an earthquake and Vesalius' grave lost to history. Modern researchers are looking into finding the lost grave and have identified the location of the cemetery. This story has not ended yet.

For a detailed biography of Andreas Vesalius CLICK HERE.

Personal note: To commemorate Andrea Vesalius' 500th birthday in 2014, there were many scientific meetings throughout the world, one of them was the "Vesalius Continuum" anatomical meeting on the island of Zakynthos, Greece on September 4-8, 2014. This is the island where Vesalius died in 1564. I had the opportunity to attend and there are several articles in this website on the presence of Andreas Vesalius on Zakynthos island. During 2015 I also attended a symposium on "Vesalius and the Invention of the Modern Body" at the St. Louis University. At this symposium I had the honor of meeting of Drs. Garrison and Hast, authors of the "New Fabrica". Dr. Miranda


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Right coronary artery

Heart, anterior view
Click for a larger image

The right coronary artery (RCA) is one of the two branches that arises from the ascending aorta and provide blood supply to the heart. The RCA begins at the coronary ostium, situated usually within the right sinus of Valsalva found in the aortic valve, one of the semilunar valves of the heart.

The RCA gives off in its initial course two arteries: the conus artery, which gives blood to the conus arteriosus, the outflow tract of the right ventricle, and the artery to the sinuatrial (SA) node, a component of the conduction system of the heart.

The RCA descends in the atrioventricular sulcus, giving off a series of small right ventricular branches and a couple of small right atrial branches, it then bends around the acute margin (margo acutus) and passes to the posterior surface of the heart. Just before the RCA bends posteriorly, it will give off the acute marginal artery, usually a thin, longer branch that extends towards the cardiac apex.

In its posterior trajectory the RCA gives off a couple of small posterior right ventricular arteries and then ends at the crux cordis, where the RCA gives off the posterior interventricular artery, commonly known as the posterior descending artery (PDA). The RCA will also give off the posterolateral artery, which, situated in the atrioventricular sulcus, extends the vascular territory of the RCA into the region of the left ventricle. This origin of the PDA from the RCA is subject to anatomical variation, which gives origin to the concept of coronary dominance.

Arising from the terminal portion of the RCA (sometimes from the posterolateral artery) is the artery to the atrioventricular (AV) node, another component of the conduction system of the heart. It is easily understood that stricture or stenosis of the RCA (depending on location) can then lead to damage of the conduction system of the heart.

Human heart and coronary artery anatomy and pathology are some of the many lecture topics developed and presented by Clinical Anatomy Associates, Inc.

Image property of: CAA.Inc.Artist: Victoria G. Ratcliffe