Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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Larynx

Larynx
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The term [larynx] originates from the Greek [λάρυγξ] meaning "upper windpipe or throat". Known vernacularly as "Adam's apple" or the "voice box" (not proper clinical terms), the larynx is the organ of phonation, and one of the organs found in the cervical visceral compartment. It is found immediately superior to the trachea, and anterior to the pharynx and esophagus.

It is formed by nine cartilages, three of which are median and single (epiglottis, thyroid, and cricoid cartilages), the rest being paired (arytenoid, corniculate, and cuneiform cartilages). In the accompanying image, the thyroid cartilage is depicted in blue, and the cricoid cartilage in green.

Within the larynx is a pair of musculomembranous folds, the vocal cords, which are innervated by the recurrent laryngeal nerves, branches of the Xth cranial nerve, also known as the vagus nerve. 

The thyroid gland (in purple) is related to the inferior aspect of the larynx. The gland receives its name from the thyroid cartilage of the larynx, as the Greek term [θυροειδής] (thyreoeidís) means "in the shape of an oblong-shield".

It was Andrea Vesalius who named the cricoid cartilage because of its shape. The Greek term [κρικοειδή] (krikoeidí) refers to a structure "shaped like a ring". The cricoid cartilage is a complete ring, and thus is different from the incomplete or "C" shaped rings of the trachea.

Image property of CAA Inc. Artist: Dr. Miranda