Medical Terminology Daily - Est. 2012

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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Sagittal section through the clivus of the skull demonstrating the location of the spheno-occipital synchondrosis in an infant.. Image modified from the original by Henry VanDyke Carter, MD. Public domain
Sagittal section through the clivus of the skull
demonstrating the location of the sphenooccipital
synchondrosis in an infant.

A synchondrosis (plural: synchondroses) is a type of cartilaginous joint characterized by a plate of hyaline cartilage that joins two bones. It is also known as a “primary cartilaginous joint”.

Since a synchondrosis practically has no movement, it is classified as a synarthrosis (plural: synarthroses) an immovable joint. All synchondroses are synarthrotic.

Because of the way bones mature, there are many skeletal synchondroses present while the individual matures, an important group of synchondroses are those of growth plates in long bones at the junction of the epiphysis and the body or shaft of the bone. These disappear when the individual reaches full skeletal maturity.

In the older individual there are a few synchondroses, one of them is found at the joint between the first rib and the sternum, others are found at the costochondral joint, the joint between the ribs and the costal cartilage.

There may be some synchondroses found in areas of skeletal anomalies, like the os acromiale, and tarsal coalitions.

Etymology: The word “synchondrosis” derives from the following medical terminology components: The Greek prefix [σύν] (sýn) meaning “along, with, or plus”, the Greek root term [χόνδρος] from [χόνδρος αρθρώσεων] (chóndros arthróseon), and the suffix [-osis], also Greek, meaning “condition”, “state of” or “many”. The term “synchondrosis” can be loosely interpreted as a “condition with cartilage”.

Sources:
1. “Gray’s Anatomy” Henry Gray, 1918
2. "Tratado de Anatomia Humana" Testut et Latarjet 8th Ed. 1931 Salvat Editores, Spain
3. "Gray's Anatomy" 38th British Ed. Churchill Livingstone 1995
4. "The Origin of Medical Terms" Skinner, HA 1970 Hafner Publishing Co.

Image modified from the original by Henry VanDyke Carter, MD. in the book "Grays's Anatomy" by Henry Gray FRS. Public domain