Medical Terminology Daily - Est. 2012

Medical Terminology Daily (MTD) is a blog sponsored by Clinical Anatomy Associates, Inc. as a service to the medical community. We post anatomical, medical or surgical terms, their meaning and usage, as well as biographical notes on anatomists, surgeons, and researchers through the ages. Be warned that some of the images used depict human anatomical specimens.

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A Moment in History

Georg Eduard Von Rindfleisch

Georg Eduard Von Rindfleisch
(1836 – 1908)

German pathologist and histologist of Bavarian nobility ancestry. Rindfleisch studied medicine in Würzburg, Berlin, and Heidelberg, earning his MD in 1859 with the thesis “De Vasorum Genesi” (on the generation of vessels) under the tutelage of Rudolf Virchow (1821 - 1902). He then continued as a assistant to Virchow in a newly founded institute in Berlin. He then moved to Breslau in 1861 as an assistant to Rudolf Heidenhain (1834–1897), becoming a professor of pathological anatomy. In 1865 he became full professor in Bonn and in 1874 in Würzburg, where a new pathological institute was built according to his design (completed in 1878), where he worked until his retirement in 1906.

He was the first to describe the inflammatory background of multiple sclerosis in 1863, when he noted that demyelinated lesions have in their center small vessels that are surrounded by a leukocyte inflammatory infiltrate.

After extensive investigations, he suspected an infectious origin of tuberculosis - even before Robert Koch's detection of the tuberculosis bacillus in 1892. Rindfleisch 's special achievement is the description of the morphologically conspicuous macrophages in typhoid inflammation. His distinction between myocardial infarction and myocarditis in 1890 is also of lasting importance.

Associated eponyms

"Rindfleisch's folds": Usually a single semilunar fold of the serous surface of the pericardium around the origin of the aorta. Also known as the plica semilunaris aortæ.

"Rindfleisch's cells": Historical (and obsolete) name for eosinophilic leukocytes.

Personal note: G. Rindfleisch’s book “Traité D' Histologie Pathologique” 2nd edition (1873) is now part of my library. This book was translated from German to French by Dr. Frédéric Gross (1844-1927) , Associate Professor of the Medicine Faculty in Nancy, France. The book is dedicated to Dr. Theodore Billroth (1829-1894), an important surgeon whose pioneering work on subtotal gastrectomies paved the way for today’s robotic bariatric surgery. Dr. Miranda.

Sources:
1. "Stedmans Medical Eponyms" Forbis, P.; Bartolucci, SL; 1998 Williams and Wilkins
2. "Rindfleisch, Georg Eduard von (bayerischer Adel?)" Deutsche Biographie
3. "The pathology of multiple sclerosis and its evolution" Lassmann H. (1999)  Philos Trans R Soc Lond B Biol Sci. 354 (1390): 1635–40.
4. “Traité D' Histologie Pathologique” G.E.
Rindfleisch 2nd Ed (1873) Ballieres et Fils. Paris, Translated by F Gross


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Thoracic vertebra, inferior view. The red rectangles show the location of the vertebral pedicles
Click for a larger image

[UPDATED] The word [pedicle] is a derivative from the Latin [pediculus] meaning “a small foot”, a “stem”, or a “stalk”. The Latin term [pediculus] is itself a derivative of [pes/pedis] meaning “foot”.

[Pedicle] is also used to denote structures that lie at the root of “foot” of an organ, as in the “renal pedicle” (an older anatomical term) or in the pedicle of a sessile tumor. It is also used in surgery, to denote the vascular pedicle or “stalk” of a free tissue graft.

Since a pedicle is also the “foot” of an arch, the term has also been used to denote the base of the vertebral arch. Thus explained, each vertebra has bilateral bony bridges between the vertebral body anteriorly and the laminae posteriorly. These are the vertebral pedicles, which form the lateral walls of the vertebral canal.

The vertebral pedicles have different characteristics (width, length, angulation) depending on their vertebral level. This is important for spine surgery where pedicle screws are used:

Lumbar vertebra: has a thicker, wider pedicle that tends to angulate posterolaterally
Thoracic vertebra: has a thinner pedicle that looks almost anteroposteriorly
Cervical vertebra: the pedicle is very small and thin, angles quite laterally, and forms the medial border of the transverse foramina.

The accompanying image is an inferior view of a thoracic vertebra showing the location of the vertebral pedicles. Click on the image for a larger version.

Additional information: “Vertebral pedicle anatomy in relation to pedicle screw fixation: a cadaver study” Chaynes et al. Surg  Rad Anat (2001) 23:2, 85-90
Image property of: CAA.Inc.. Photographer: D.M. Klein.